[Types of cell differentiation in colonic and rectal adenocarcinoma]

The Normal mucous membrane and tumours of the large intestine and the rectum were studied electron microscopically. Five known cell types were found in normal intestinal mucosa: intestinal epitheliocyte with striated border, goblet enterocyte, intestinal argentaffinocyte, enterocyte with acidofilic granules, borderless enterocyte. Adenocarcinoma cells differentiate in the direction of 3 cell types: intestinal epitheliocytes, goblet enterocytes, and borderless enterocytes. The level of differentiation in different cells varies considerably.