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Updated: Sep 3, 2026
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Quantitative Immunohistochemistry of the Cellular Microenvironment in Patient Glioblastoma Resections
Published on: July 31, 2017
Immunohistochemistry as a tool for identifying PDGFRA amplification in central nervous system tumors
Arnault Tauziède-Espariat1, Guilhem Amargos1, Farah Sassi1
1Department of Neuropathology, GHU Paris - Psychiatry and Neurosciences, Sainte-Anne Hospital, Paris, France.
Brain Pathology (Zurich, Switzerland)
|September 2, 2026
Abstract:
PDGFRA gene amplification is now recognized as a diagnostically and prognostically relevant molecular alteration in central nervous system tumors. Herein, we demonstrated that PDGFRA immunohistochemistry is a highly specific and sensitive biomarker for identifying PDGFRA amplification and should be part of the neuropathologist's routine panel of antibodies.
