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Updated: Sep 4, 2026
Magnetic-, Acoustic-, and Optical-Triple-Responsive Microbubbles for Magnetic Hyperthermia and Pothotothermal Combination Cancer Therapy
Published on: May 22, 2020
Size-dependent surface engineering of magnetic micro/nanorobots for synergistic chemo-magnetothermal cancer therapy
Ying Feng1,2,3, Linlin Liu1,2,3, Yang Liu1,2,3
1Engineering Research Center of Nano-Geomaterials of Ministry of Education, China University of Geosciences, Wuhan 430074, China. hm.yang@cug.edu.cn.
Abstract:
Size-tunable magnetite micro/nanorobots (MNRs) loaded with doxorubicin (DOX) exhibit targeted locomotion and enable synergistic chemo-magnetothermal therapy for cancer cells. In vitro studies show enhanced cancer cell killing, reactive oxygen species (ROS) generation, and mitochondrial disruption, with smaller nanoparticles achieving superior cellular internalization. This promising strategy effectively overcomes limitations of monotherapies.
