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Updated: Sep 6, 2026
Evaluation of Capillary and Other Vessel Contribution to Macular Perfusion Density Measured with Optical Coherence Tomography Angiography
Published on: February 18, 2022
Optical Coherence Tomography Angiography in Pediatric Myopia and Amblyopia: A Review of Clinical Applications,
Jiajun Wang1, Daohuan Kang1, Huixia Hua1
1Department of Ophthalmology, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center For Children And adolescents' Health and Diseases, No.3333, Binsheng road, Binjiang District, Hangzhou, 310003, China.
Abstract:
Optical Coherence Tomography Angiography (OCTA) provides depth-resolved imaging of the retinal vascular system without invasion. Its rapid and non-invasive characteristics make it a promising tool for pediatric retinal imaging. Pediatric myopia and amblyopia can affect visual development and long-term visual prognosis. Early identification and dynamic monitoring are of great clinical significance. This paper retrieved English literature published from January 2006 to May 2026 in PubMed and Web of Science, and reviewed the application of OCTA in pediatric myopia and amblyopia. Existing studies show that pediatric myopia is characterized by decreased retinal vascular density (VD), thinner choroidal thickness (CT), and changes in choroidal perfusion parameters; amblyopia is mainly manifested as decreased retinal VD, but results for the foveal avascular zone (FAZ) and choroidal-related indicators are inconsistent. At present, there are still some deficiencies in the research, such as limited sample size, non-uniform equipment and scanning protocols, and lack of long-term follow-up. OCTA is expected to become an important auxiliary tool for the diagnosis, evaluation, and monitoring of treatment for childhood myopia and amblyopia.