Genomic competence in nurse practitioner practice: Bridging the gap between knowledge and clinical application

Genomics is increasingly integral to nurse practitioner (NP) practice, informing risk assessment, diagnosis, treatment selection, and precision care. Despite expanded clinical responsibilities, recent evidence demonstrates that NP genomic knowledge remains only moderate, mirroring earlier findings among registered nurses. This persistent gap highlights the need to move beyond foundational education toward applied, practice-based genomic competency. In addition to strengthening workforce preparedness, NPs must advocate for equitable access to genomic services through organizational, state, and federal policy initiatives. Advancing genomic competence and advocacy is essential to improving patient outcomes, reducing disparities, and ensuring equitable implementation of precision health care.