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Updated: Sep 12, 2026

Structure-Guided Design and Development of Novel Cyclophilin A Inhibitors and Ganoderiol-F Derivatives: An In-Silico Approach
10:01

Structure-Guided Design and Development of Novel Cyclophilin A Inhibitors and Ganoderiol-F Derivatives: An In-Silico Approach

Published on: June 23, 2026

Structural basis of Nur77-CypA interaction and cyclosporine A-mediated competitive displacement

Lang Chen1, Jiawen Chen2, Wenkai Zhu2

  • 1State Key Laboratory of Magnetic Resonance Spectroscopy and Imaging, National Center for Magnetic Resonance in Wuhan, Wuhan National Laboratory for Optoelectronics, Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences, Wuhan, 430074, China; University of Chinese Academy of Sciences, Beijing, 100049, China.

Biochemical and Biophysical Research Communications
|September 9, 2026
PubMed

Keywords:
Cyclosporine ACypANMRNuclear receptorNur77Protein-protein interaction

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