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Updated: Sep 11, 2026

Transplantation of a 3D Bioprinted Patch in a Murine Model of Myocardial Infarction
Published on: September 26, 2020
Early Biological Reaction to a Synthetic Hybrid Patch Inducing Tissue Ingrowth as a Senning Atrial Baffle
Akira Yamaguchi1, Hiroomi Murayama1, Shintaro Nemoto2
1Department of Cardiovascular Surgery, Kids' Heart Center, Aichi Children's Health and Medical Center, Aichi, Japan.
Abstract:
We report a case in which a new synthetic hybrid patch inducing autologous tissue ingrowth was used to replace the obstructed Senning atrial baffle in a double switch operation for congenitally corrected transposition of the great arteries. However, recurrent baffle obstruction developed after 10 months postoperatively and was removed. Histology of the excised specimen showed promising tissue ingrowth but cautionary peripheral folding of the patch in this clinically challenging condition.

