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Characterisation of the MICA*045:01:04 and MICA*004:01:22 Alleles in Haematopoietic Stem Cell Donors From India

Disha Agarwal1, Gaurav Sharma1, Alka Khadwal2

  • 1Department of Translational and Regenerative Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

HLA
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For the same gene multiple alleles can interact to influence phenotypes like the shape and protein composition of an individual cells.By studying allele interactions on the molecular and cellular levels researchers can understand the resulting phenotypes and complications of human conditions like sickle cell trait, improving treatment.The ABO blood group system is a common example of multiple alleles in humans. This system includes three alleles called IA, IB, and i alleles, which combine in...