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Updated: Sep 19, 2026
06:51
Techniques to Induce and Quantify Cellular Senescence
Published on: May 1, 2017
Deciphering senescence-associated mechanisms through cell painting & transcriptomics
Yuliana Tan1, Anika Liu2, Emily Larkin2,3
1Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach an der Riβ, Germany. yuliana.tan@boehringer-ingelheim.com.
Npj Aging
|September 17, 2026
Abstract:
Senescence is a key pathomechanism across chronic diseases but also highly heterogeneous. In this study, we demonstrate that high-content imaging and transcriptomics can jointly shed light on senescence in vitro, distinguishing replicative and chemically induced senescence, differentiating from quiescence and characterizing the senolytic response.
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