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Characterisation of the Novel HLA-C*16:01:53 Allele by Next-Generation Sequencing

Delphine Giusti1, Grégory Salez2, Thierry Tabary2

  • 1Université de Reims Champagne-Ardenne, IRMAIC, CHU Reims, Laboratoire d'Immunologie, Pôle de biologie médicale et pathologie, Reims, France.

HLA
|September 18, 2026
PubMed

Keywords:
HLA‐C*16:01:53HLAnext‐generation sequencingnovel allele

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Next-generation Sequencing03:00

Next-generation Sequencing

The first human genome sequencing project cost $2.7 billion and was declared complete in 2003, after 15 years of international cooperation and collaboration between several research teams and funding agencies. Today, with the advent of next-generation sequencing technologies, the cost and time of sequencing a human genome have dropped over 100 fold.
Next-Generation Sequencing Methods
Although all next-generation methods use different technologies, they all share a set of standard features.