Related Experiment Video
Updated: Aug 7, 2026

10:19
A Murine Model of Group B Streptococcus Vaginal Colonization
Published on: November 16, 2016
Bovine granular vulvitis associated with ureaplasma infection
Summary
Ureaplasma infection causes granular vulvitis in dairy cows, impacting fertility. Tetracycline treatment improved conception rates in acutely affected herds, offering a potential solution for this bovine reproductive issue.
Area of Science:
- Veterinary Medicine
- Bovine Health
- Infectious Diseases
Background:
- Granular vulvitis syndrome, linked to Ureaplasma infection, was identified in Ontario dairy cattle in 1972.
- The disease presents in acute and chronic forms, with distinct clinical signs including vulvar discharge and mucosal inflammation.
Purpose of the Study:
- To describe the characteristics of granular vulvitis syndrome in dairy herds.
- To investigate the impact of the disease on herd fertility.
- To evaluate the efficacy of tetracycline treatment on conception rates.
Main Methods:
- Clinical observation of acute and chronic granular vulvitis in dairy cows.
- Fertility data analysis, including first service conception rates.
- Evaluation of intrauterine tetracycline infusions post-breeding.
Main Results:
- Acute granular vulvitis featured purulent discharge and hyperemia; chronic form lacked discharge but showed reduced inflammation.
- Seasonal variation in incidence was noted, with higher morbidity during winter housing (75%) versus summer (37%).
- First service conceptions decreased by 27% in acute cases and 13% in chronic cases; tetracycline improved rates in acute herds.
Conclusions:
- Ureaplasma-associated granular vulvitis significantly affects dairy herd fertility.
- Seasonal housing patterns influence disease incidence.
- Intrauterine tetracycline administration shows promise for improving fertility in affected herds.
Related Concept Videos
Sexually Transmitted Infections
Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
Urinary Tract Infection I: Introduction
Urinary tract infections (UTIs) impact various parts of the urinary system, including the kidneys, ureters, bladder, and urethra. These infections are generally bacterial, with Escherichia coli being the most common causative agent, often originating from the gastrointestinal tract. However, other bacteria, such as Staphylococcus saprophyticus, Klebsiella pneumoniae, and Proteus mirabilis, are also known to cause UTIs. The type, location, and underlying complexity of the UTI guide both...
Urinary Tract Infection II: Pathophysiology
The pathophysiology of urinary tract infections (UTIs) encompasses several progressive stages, beginning with bacterial colonization and culminating in potential systemic complications if untreated. UTIs are primarily initiated by bacteria, such as Escherichia coli, which often originate from the gastrointestinal tract and migrate to the urinary system through the periurethral area. This migration can occur via several routes, including improper hygiene practices, sexual activity, or...
Microbiota of the Urogenital Tract
The human urogenital system, once thought to be sterile in healthy individuals, is now recognized as a complex microbial habitat. Advancements in molecular sequencing techniques have revealed that even in healthy adults, the kidneys and bladder harbor microbial populations similar to those found in the distal urethra, albeit in much lower abundance. These resident microorganisms, while generally innocuous, can become opportunistic pathogens under conditions that alter the urogenital...
Genital Herpes
Genital herpes is a sexually transmitted infection primarily caused by herpes simplex virus type 2 (HSV-2), though herpes simplex virus type 1 (HSV-1) is increasingly implicated in genital infections, particularly among younger populations. Transmission occurs mainly through sexual contact, with asymptomatic viral shedding serving as a major route of spread. This characteristic makes HSV-2 difficult to control at a population level, as individuals may unknowingly transmit the virus even in the...
Trichomoniasis
Trichomonas vaginalis is a flagellated protozoan parasite and the causative agent of trichomoniasis, one of the most prevalent non-viral sexually transmitted infections in the United States. This extracellular parasite primarily colonizes the lower genitourinary tract in women—particularly the vagina—and in men, the urethra and prostate. Its structural and functional adaptations enable its survival, motility, and pathogenicity within the host environment.Structural Features and Host EntryT.

