Re-Review Summary of Ascorbic Acid and Ascorbates
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Updated: Sep 24, 2026

A Rapid and Specific Microplate Assay for the Determination of Intra- and Extracellular Ascorbate in Cultured Cells
Published on: April 11, 2014
Priya Ferguson1, Wilma F Bergfeld2, Donald V Belsito2
1Cosmetic Ingredient Review Associate Toxicologist & Senior Scientific Analyst/Writer.
Abstract:
The Expert Panel for Cosmetic Ingredient Safety (Panel) considered whether the safety of l-Ascorbic Acid, Calcium Ascorbate, Magnesium Ascorbate, Magnesium Ascorbyl Phosphate, Sodium Ascorbate, and Sodium Ascorbyl Phosphate as used in cosmetics should be reassessed. The Panel reviewed newly available safety data related to these ingredients. The Panel concluded, based on the available data contained in the report, that these 6 ingredients are safe as cosmetic ingredients in the present practices of use and concentration as described in the report.
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