Related Experiment Videos
ADVANCES IN THE GENETICS AND IMMUNOLOGY OF PSORIASIS
Andrea Leung1, Georgia Marquez-Grap1, Allison Kranyak1
1Department of Dermatology, University of California San Francisco, San Francisco, CA.
Abstract:
Psoriasis is a chronic, immune-mediated skin condition characterised by keratinocyte hyperproliferation and T cell activation. Prior research has revealed environmental and genetic associations that have contributed to the understanding of psoriasis pathophysiology. Further, this research has contributed to advancements in diagnostics, risk stratification, and therapeutics that impact patient care and health outcomes in psoriasis-associated comorbid conditions such as psoriatic arthritis, metabolic syndrome, and hypertension. Here we review recent advances in psoriasis genetics and immunology.
Related Concept Videos
iPS Cell Differentiation
T Cell Types and Functions
Th1 cells stimulate dendritic cells to express necessary co-stimulatory molecules on their surfaces for...
Pharmacogenomics: Identification of New Drug Targets
EPS and iPS Cells in Disease Research
Autoimmune Disorders
Concept and Mechanism of Autoimmune Diseases
The immune system...
Skin Diseases and Disorders
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...