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Screening for Melanoma Modifiers using a Zebrafish Autochthonous Tumor Model
Published on: November 13, 2012
Silicoanthracosis: A melanoma mimicker
Sajanakan Sriselvakumar1, Marion Hanley1, Gurjeet Dulku1
1Medical Imaging Department, Fiona Stanley Hospital, Murdoch, Australia.
Abstract:
Silicoanthracosis is a type of fibrotic lung disease resulting from prolonged inhalation of silica particles. The silica particles can trigger an inflammatory response resulting in subsequent fibrotic changes which may lead to anthracotic black pigmentation of the airways or lymph nodes. We present the interesting case of an incidental finding of lymphadenopathy related to silicosis with surprising visible black pigmentation of the biopsied specimen, an important differential diagnosis for visibly pigmented lymph nodes.
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