Related Experiment Video

Updated: Oct 5, 2026

Deficient Pms2, ERCC1, Ku86, CcOI in Field Defects During Progression to Colon Cancer
28:15

Deficient Pms2, ERCC1, Ku86, CcOI in Field Defects During Progression to Colon Cancer

Published on: July 28, 2010

Correction: The crotonylation reader DPF2 promotes the development and progression of colon adenocarcinoma through

Jingzhi Wang1,2, Jingyi Zhou1, Lin Liu1

  • 1Department of Oncology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, Jiangsu, China.

Frontiers in Pharmacology
|October 3, 2026
PubMed

Keywords:
DPF2colon adenocarcinomacrotonylationmetabolic reprogrammingtumor immune microenvironment

Related Concept Videos

Tumor Progression02:07

Tumor Progression

Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...