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Updated: Oct 9, 2026

Quantification of Reactive Oxygen Species Using 2′,7′-Dichlorofluorescein Diacetate Probe and Flow-Cytometry in Müller Glial Cells
Published on: May 13, 2022
Oxidative stress and glycosylation in viral infection and inflammatory response
Sanchita Chakraborty1, Anand Kasirajan1, Agiesh Kumar Balakrishna Pillai2
1Mahatma Gandhi Medical Advanced Research Institute (MGMARI), Sri Balaji Vidyapeeth (Deemed to be University), Puducherry, India.
Abstract:
Reactive oxygen species (ROS) act as key intracellular signaling molecules, especially during infection and inflammation. Increased ROS disrupts cellular processes and worsens infectious disorders. While redox-related patterns are observed in several viral diseases, few studies examine redox and glycan metabolism. Glycans are sugar chains on cell and viral surfaces that influence viral entry and immune recognition. Studying glycan pathways under oxidative stress may enable new therapies. This review discusses an overview on the interactions between the host key regulators like of the ROS-driven oxidative stress like Nrf2 and NLRP3, and the antiviral host guanylate binding protein 5 (GBP5) during the viral infections and their impact on glycosylation.
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