Related Experiment Video
Updated: Oct 9, 2026

Surveying Low-Cost Methods to Measure Lifespan and Healthspan in Caenorhabditis elegans
Published on: May 18, 2022
Against the "extend healthspan but not lifespan" cliché
David Gems1, Ekaterina R Iijima2, João Pedro de Magalhães3
1Institute of Healthy Ageing, and Research Department of Genetics, Evolution and Environment, University College London, London, WC1E 6BT, UK. david.gems@ucl.ac.uk.
Abstract:
What is the ultimate goal of biogerontology (the study of the biology of aging)? A fashionable answer these days, often encountered, is that it is to extend healthspan not lifespan. Here we argue that this is a misguided cliché. Experimental research with animal models has demonstrated the possibility of intervening in and retarding the aging process, and extending lifespan. This, to varying degrees, increases both healthspan and gerospan, the later-life phase in diminished health. Considering possible equivalent interventions in human aging it would of course be desirable to maximize the former and minimize the latter. However, should a given intervention extend gerospan, given that it would postpone death (i.e., save lives) it would, in many circumstances, be unethical to withhold it. Life in moderately diminished health is generally preferable to death, and this is reflected in the recognized value of many life-saving medical interventions that do not restore full health. Thus, "extending healthspan but not lifespan" is not a coherent objective for research on aging.
Related Concept Videos
Replicative Cell Senescence
Replicative Cell Senescence
Energy Budgets and Reproductive Strategies
Life Histories
Aging
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
Principles of the Life-Span Developmental Approach: Part 1

