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Updated: Oct 10, 2026

Cell-Based Drug Screening for Inhibitors of Autophagy Related 4B Cysteine Peptidase
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Cell-Based Drug Screening for Inhibitors of Autophagy Related 4B Cysteine Peptidase

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Disrupting BRD4-BD1-p62 engagement restores protective autophagy

Jifa Zhang1, Yu Cao1, Chengyong Wu1

  • 1Department of Biotherapy, State Key Laboratory of Biotherapy and Cancer Center, Laboratory of Neuro-system and Multimorbidity, Department of Respiratory and Critical Care Medicine, Center for High Altitude Medicine, Children's Medicine Key Laboratory of Sichuan Province, West China Hospital, Sichuan University, Chengdu 610041, Sichuan, P.R. China.

Cell Chemical Biology
|October 8, 2026
PubMed

Keywords:
BRD4-BD1co-crystal structureidiopathic pulmonary fibrosisprotective autophagyselective inhibitor

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