Related Experiment Video
Updated: Oct 19, 2026

Integrated Photoacoustic Ophthalmoscopy and Spectral-domain Optical Coherence Tomography
Published on: January 15, 2013
Spectrometer matching for balanced detection in spectral-domain optical coherence tomography by autocorrelation
Santosh Balakrishnan1, Steven G Adie1
1Nancy E. and Peter C. Meinig School of Biomedical Engineering, Cornell University, Ithaca, New York 14850, USA.
Abstract:
Precise matching of spectrometers is essential to realizing the full benefits of balanced detection in spectral-domain optical coherence tomography (SD-OCT). A retrospective approach to match spectrometers, based on the observation that the autocorrelation signal should be zero in a perfectly balanced system, is presented. This approach requires only a single calibration B-scan, does not depend on the source noise or image properties, and can be used either to guide alignment or to obtain balanced results from previously acquired data. The performance of this method is demonstrated on a fiber-based SD-OCT system with a pair of commercial spectrometers and for a super-luminescent diode or supercontinuum laser source.
More Related Videos
Related Concept Videos
Attenuated Total Reflectance (ATR) Infrared Spectroscopy: Overview
The ATR process begins by directing a beam...
Atomic Absorption Spectroscopy: Interference
Spectral interference occurs when signals from other elements or molecules overlap with the analyte signal, falsely elevating or masking the analyte's absorbance. This interference can be corrected using Zeeman,...
Raman Spectroscopy Instrumentation: Overview
The monochromatic laser source, typically using visible or near-infrared radiation, generates a highly focused beam of light. This light interacts with the molecules of the sample, scattering some of the light. Liquid and gaseous samples are usually tested in ordinary glass capillaries, while solids can be analyzed as powders packed in capillaries or as potassium...
Atomic Absorption Spectroscopy: Instrumentation
The atomizer used in AAS can be either a flame atomizer or an...
IR Spectrometers
UV–Vis Spectroscopy: Woodward–Fieser Rules

