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Updated: Oct 25, 2026

Robotic-assisted Bronchoscopy Combined with Multimodal Imaging for Targeted Lung Cryobiopsies
Published on: July 19, 2024
Broncholith Removal Using a Cryoprobe in Combination With Biopsy Forceps in a Patient With Immune Thrombocytopenia: A
Qisheng Xiao1, Nan Ma1, Jianbo Zhu1
1Department of Respiratory and Critical Care Medicine Binzhou People's Hospital Affiliated to Shandong First Medical University Binzhou Shandong China.
Abstract:
Broncholithiasis is a rare respiratory condition usually caused by calcified lymph nodes eroding into the bronchial lumen, often following pulmonary tuberculosis or histoplasmosis infections. Patients may be asymptomatic or present with haemoptysis, recurrent respiratory infections or airway obstruction, for which bronchoscopic or surgical treatment may be required. No internationally standardized guidelines currently exist for broncholith removal. We report a 63-year-old woman with previous pulmonary tuberculosis, recurrent haemoptysis and thrombocytopenia that was subsequently diagnosed as immune thrombocytopenia. Chest CT showed a 9 × 8 mm calcified lesion in the distal anterior segmental bronchus of the right upper lobe. Bronchoscopy revealed a transbronchial broncholith surrounded by granulation tissue and firmly attached at its base. The broncholith was removed using a cryoprobe and biopsy forceps under flexible bronchoscopy, with minor bleeding. This case suggests that broncholith removal under flexible bronchoscopy using a cryoprobe combined with biopsy forceps may be feasible in patients with thrombocytopenia.