Related Experiment Video
Updated: Oct 25, 2026

Single-molecule Manipulation of G-quadruplexes by Magnetic Tweezers
Published on: September 19, 2017
Toward a Local Manipulation of DNA by Quantum Fields
Tommaso Cenci1, Riccardo Alessandro1, Enrico Ronca1
1Dipartimento di Chimica, Biologia e Biotecnologie, Università degli Studi di Perugia, 06123Perugia, Italy.
Abstract:
Hydrogen bonds are the fundamental backbone for deoxyribo-nucleic acid (DNA) stability. In this Letter we investigate a new strategy based on plasmonic cavities to perform manipulation of hydrogen bonds in DNA. The analysis is performed using state-of-the-art Quantum Electrodynamics Coupled Cluster (QED-CC) calculations. We investigate whether in the strong coupling regime modifications of the nucleotide bases' interactions can be induced in a totally nonintrusive manner. Our strategy proposes an alternative approach to methodologies based on a collective coupling to perform optical DNA manipulation.
Related Concept Videos
DNA Topoisomerases
Types and Mechanism of action
Topoisomerases are divided into two main types. Type I...
Transformation
Conservative Site-specific Recombination and Phase Variation
The recognition sites for Cre recombinase called LoxP...
Recombinant DNA
The Quantum-Mechanical Model of an Atom

