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Scanning Light Scattering Profiler (SLPS) Based Methodology to Quantitatively Evaluate Forward and Backward Light Scattering from Intraocular Lenses
Published on: June 6, 2017
Improving effective lens position prediction for secondary intraocular lens implantation in pediatric aphakic eyes
Jiaxin Jin1, Yiwen Qu1, Guangming Jin1
1State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases, Guangzhou, 510060, China.
Purpose:
To improve the accuracy of refractive prediction for pediatric secondary sulcus intraocular lens (IOL) implantation by optimizing the effective lens position (ELP) prediction within the SRK/T formula.
Setting:
Zhongshan Ophthalmic Center, Guangzhou, China.
Design:
Retrospective consecutive case-series.
Methods:
The value of sulcus-ELP was identified by linear regression formula with utilizing back-calculated ELP. The obtained sulcus-ELP was subsequently incorporated into the original SRK/T formula, then creating the sulcus-SRK/T formula. The prediction accuracy of sulcus-SRK/T formula was compared with six formulas. Main outcome measures included prediction error (PE), mean error (ME), median absolute error (MedAE), and the percentage of eyes with prediction error within ±0.50 diopters (D) and ±1.00 D.
Results:
This study included 86 pediatric patients (131 eyes) who underwent secondary ciliary sulcus IOL implantation. With the modified formula, the percentages of eyes achieving the prediction error (PE) within ±0.50 D and ±1.00 D were 25.6% and 53.9%, respectively, significantly higher than those of other formulas. The mean error (ME) of the modified formula was 0.46±1.39 D, and the modified formula showed lower median absolute error (MedAE) (0.95 D, P < .05) than other formulas.
Conclusions:
By optimizing ELP prediction of the SRK/T formula, the prediction accuracy of pediatric secondary sulcus IOL implantation has been improved. The sulcus-SRK/T formula is a worthwhile choice and requires further external validation to confirm its effectiveness.