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Updated: Oct 25, 2026

Treatment of Liver Metastases Using an Internal Target Volume Method for Stereotactic Body Radiotherapy
Published on: May 8, 2018
Liver transplantation as a treatment option for neuroendocrine liver metastases: a systematic review
Isabel Jaén-Torrejimeno1,2, Diego López-Guerra1,2,3, Adela Rojas-Holguín1,2,3
1Servicio de Cirugía Hepatobiliopancreática y Trasplante Hepático, Complejo Hospitalario Universitario de Badajoz.
Objetive:
The aim was to carry out a systematic review of published articles on liver transplantation outcomes in patients with (LM-NET).
Methods:
We performed a systematic review according to the PRISMA guideline guidelines, using the MEDLINE (PubMed) and Scopus databases to identify published studies.
Results:
We included 2471 articles after the search, finally selecting 25. We collected data from 1005 patients, with a mean age of 47.9 years, most of them male. The most frequent locations of the primary tumor were the pancreas, followed by the small intestine. The disease-free survival was 25.3 months (14-31) and overall survival 38.5 months (32.5-57.1).
Conclusions:
Liver transplantation appears to provide a survival benefit in patients with diffuse LM-NET without extrahepatic disease in selected cases.

