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A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones
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A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones

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Direct C2 Acylation of Free (N-H) Indoles Enabled by Pd(II)/Norbornene Cooperative Catalysis

Ying Liu1, Yutong Sun2, Wenlin Zhang1

  • 1School of Pharmacy, Xianning Medical College, Hubei University of Science and Technology, Xianning437100, P. R. China.

Organic Letters
|October 23, 2026
PubMed

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