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Updated: Oct 25, 2026

Synthesis of Hypervalent Iodonium Alkynyl Triflates for the Application of Generating Cyanocarbenes
Published on: September 8, 2013
HBr-Catalyzed Construction of Sulfur-Containing Heterocycles via Difunctionalization of Alkenes
Chao Xie1, Zemin Wang1, Shuhan Zhu1
1State Key Laboratory of Microbial Technology, Shandong University, Qingdao266237, China.
Abstract:
Sulfur-containing heterocycles are important chemical entities and key structural motifs in many biologically active molecules, representing valuable but synthetically challenging building blocks. Herein, we report a new method for the construction of sulfur-containing heterocycles under mild conditions using a green oxidative system composed of HBr and DMSO. This transformation employs inexpensive and readily available thiophenols as the sulfur source, operates without external photocatalysts and metals, and offers a general approach for the construction of small-ring and bridged-ring systems.
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