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Updated: Oct 25, 2026

Microwave-assisted Intramolecular Dehydrogenative Diels-Alder Reactions for the Synthesis of Functionalized Naphthalenes/Solvatochromic Dyes
Published on: April 1, 2013
Iodoform-Catalyzed Intramolecular Dehydrogenative C(sp3)-N Bond Formation toward Dihydropyrazoles
Pengpeng Zhu1, Siwen Chen1, Yujie Zhi1
1Jiangsu Provincial Key Laboratory of Green & Functional Materials and Environmental Chemistry, School of Chemistry & Materials, Yangzhou University, Yangzhou225002, China.
Abstract:
We report herein a visible-light photochemical intramolecular dehydrogenative coupling strategy enabling C(sp3)-N bond formation for the synthesis of aza-heterocycles with a catalytic amount of the iodoform and the benzoyl peroxide (BPO) oxidant. The utilization of β-aryl ketone-derived N-sulfonylhydrazones as the substrates allows direct benzylic C(sp3)-N bond formation, providing an efficient protocol for the synthesis of dihydropyrazoles.
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