Risk factors for diabetic peripheral neuropathy in diabetes mellitus patients: A case-control study

Diabetes mellitus is a chronic metabolic illness that can lead to complications such as Diabetic Peripheral Neuropathy (DPN). Identifying risk factors for DPN is crucial for prevention and management. The study aims to enhance understanding of the underlying mechanisms contributing to DPN and to inform targeted interventions that can improve patient outcomes.

This study utilized a quantitative, case-control design involving 108 patients with diabetes mellitus at the Regional Hospital Dr. Moewardi. Members were alienated hooked on two groups: those with diabetic motor neuropathy and those without. Data were collected through direct physical examinations and questionnaires assessing smoking history, duration of diabetes, education level, and self-management compliance. Statistical analyses, including Chi-square tests and logistic reversion, were performed to evaluate the relationships between these factors and the incidence of DPN.

The analysis revealed a statistically significant association between self-management compliance and DPN (OR = 3.667, 95% CI: 2.262-5.954, P < 0.001), with non-compliant individuals having 3.67 times higher odds of developing DPN compared to compliant individuals. Education level (P = 0.098) and duration of illness (P = 0.313) were examined as risk factors but did not reach statistical significance, while no statistically significant relationship was found between smoking status and DPN (P = 1.000).

The findings highlight the critical role of self-management in preventing DPN among diabetes patients. Improving self-management compliance is essential to reduce the risk of neuropathy and its complications, emphasizing the need for targeted interventions in diabetes care.