Rhabdomyosarcoma of the Cervix/Vagina and Its Mimics
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Updated: Oct 30, 2026

An Orthotopic Endometrial Cancer Model with Retroperitoneal Lymphadenopathy Made From In Vivo Propagated and Cultured VX2 Cells
Published on: September 12, 2019
1James Homer Wright Pathology Laboratories, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Abstract:
Rhabdomyosarcomas form a morphologically and genomically heterogeneous family of malignant mesenchymal tumors defined by skeletal muscle differentiation. In the gynecologic tract, the same morphologic subtypes defined at extragenital sites may be encountered, but there are unique genetic associations and differential diagnostic concerns which should be addressed. This article aims to clarify the pathologic assessment of gynecologic rhabdomyosarcomas and their mimics, particularly in the cervix and vagina.
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