Membrane stripping alone for suspected ocular argyrosis: A novel therapeutic approach

To report two cases of suspected ocular argyrosis and discuss their management.

Ocular argyrosis is a rare condition resulting from chronic silver exposure, typically manifesting as grayish corneal deposits at the level of Descemet's membrane and conjunctiva. It is often associated with systemic argyria in individuals with occupational exposure to silver compounds. Current literature lacks consensus on treatment, with most cases reporting long term retinal damage due to the condition. Vision loss is associated with the concurrent macular damage, and cataractous lens changes. In this report, we describe the clinical presentation, histopathology, and surgical management of ocular argyrosis.

Conservative approach like a Membrane stripping alone for visual rehabilitation might work in cases of ocular argryrosis, eliminating the need for a keratoplasty.