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Related Experiment Videos

A controlled field study using live virus vaccines and an antiserum in a preconditioning program.

G T Woods, M E Mansfield, J Krone

    Canadian Journal of Comparative Medicine : Revue Canadienne De Medecine Comparee
    |January 1, 1972
    PubMed
    Summary

    Vaccinating beef calves against infectious bovine rhinotracheitis (IBR) and bovine virus diarrhea (BVD) before shipment improves weight gain. Pre-shipment vaccination timing is crucial for preventing respiratory disease in feedlot cattle.

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    Area of Science:

    • Veterinary Immunology
    • Bovine Respiratory Disease
    • Vaccinology

    Background:

    • Bovine respiratory disease (BRD) is a significant concern in feedlot cattle.
    • Vaccination strategies aim to mitigate BRD caused by infectious bovine rhinotracheitis (IBR), bovine virus diarrhea (BVD), and bovine parainfluenza 3 (PI3).

    Purpose of the Study:

    • To evaluate the efficacy of different vaccination protocols and antiserum administration on immune response and performance in beef calves.
    • To determine optimal timing for pre-shipment vaccination against IBR and PI3.

    Main Methods:

    • Study involved 35 vaccinated and 29 control beef calves across five farms.
    • Multiple vaccination groups received modified live or live virus vaccines against IBR, BVD, and PI3 at varying times relative to shipment.

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  • One group received antiserum followed by vaccination; control calves received no treatment.

    • Main Results:

    • Seroconversion to BVD occurred in all vaccinated groups.
    • Clinical BVD affected one calf in group 2 and eight in group 5.
    • Calves vaccinated before shipment showed significantly higher weight gains compared to controls.
    • Antiserum provided no apparent advantage over controls in preventing respiratory disease.

    Conclusions:

    • Vaccination against IBR and PI3 should be administered at least 17 days before shipment to feedlots with known infected cattle.
    • Pre-shipment vaccination timing is critical for improving feedlot performance.
    • Antiserum is not advantageous for preventing clinical respiratory disease in this context.