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Related Experiment Videos

Gentian violet keratoconjunctivitis.

W T Parker, P S Binder

    American Journal of Ophthalmology
    |March 1, 1979
    PubMed
    Summary
    This summary is machine-generated.

    Gentian violet eye drops can cause severe ocular surface toxicity, leading to complications like uveitis and corneal damage. Prompt treatment is crucial for managing these adverse effects.

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    Area of Science:

    • Ophthalmology
    • Toxicology

    Background:

    • Gentian violet is a cationic dye used topically for various conditions.
    • Ocular toxicity from self-administered gentian violet is not well-documented.

    Observation:

    • A case of bilateral keratoconjunctivitis resulted from self-instilling 1% aqueous gentian violet.
    • The condition was complicated by secondary uveitis and gram-negative conjunctivitis.

    Findings:

    • Treatment involved cycloplegics, antibiotics, and topical corticosteroids.
    • While keratitis resolved, sequelae included corneal vascularization, posterior synechiae, scarring, and cataract formation.

    Implications:

    • Cationic dyes like gentian violet exhibit ocular surface toxicity.
  • These dyes can induce severe intraocular inflammation, necessitating cautious use.