Failure to demonstrate antigonadotrophic activities of arginine vasotocin in the mouse

Arginine vasotocin (AVT) has previously been proposed to be a pineal hormone which reduces reproductive competency in mammals. The effects of AVT on the growth of immature reproductive organs of the mouse have been studied using blind study techniques. Evidence is presented which fails to support the proposed role of AVT as a mammalian antigonadotrophin.