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The recurrence of intracranial meningiomas
Abstract:
A series of 126 patients with meningioma, operated upon 7-17 years ago, is reviewed as to the recurrence of the tumour. The overall rate of recurrence of the histologically benign lesions was 29 per cent. The most important factors influencing the prognosis were the site of the tumour and the degree of radicality of excision. Both factors were illustrated best in the parasagittal meningiomas, which carry the highest rate of recurrence. Infiltration of tumour into adjacent bone does not necessarily carry a higher risk of a clinically relevant recurrence. There seems to be a great variation in the rate of growth of different meningiomas.
Insights
Recurrence rates for benign meningioma tumors after surgery were 29%. Tumor site and surgical removal extent significantly impact recurrence risk, especially for parasagittal meningiomas.
Area of Science:
- Neurosurgery
- Oncology
- Pathology
Background:
- Meningiomas are the most common primary intracranial tumors.
- Understanding recurrence patterns is crucial for patient management and prognosis.
Purpose of the Study:
- To analyze the recurrence rates of meningioma after surgical intervention.
- To identify key factors influencing tumor recurrence and long-term prognosis.
Main Methods:
- Retrospective review of 126 patients with meningioma operated on 7-17 years ago.
- Analysis of recurrence based on tumor histology, site, surgical radicality, and bone infiltration.
Main Results:
- Overall recurrence rate for benign meningiomas was 29%.
- Tumor site and extent of surgical excision were significant prognostic factors.
- Parasagittal meningiomas exhibited the highest recurrence rates.
- Bone infiltration did not correlate with increased risk of clinically relevant recurrence.
Conclusions:
- Meningioma recurrence is influenced by tumor location and surgical completeness.
- Parasagittal meningiomas require particular attention due to higher recurrence potential.
- Individual meningioma growth rates vary significantly.