Related Experiment Videos
Abstract:
Histones form insoluble complexes with heparin and neutralize its anticoagulant action. The plasmin degradation products of histones do not possess these properties. Plasmin also digests histones in complexes with heparin. Breakdown of the histones in these complexes causes release of heparin from them.
Related Concept Videos
Articles linked to this work by shared authors, journal, and citation graph.
Lactacystin inhibits cathepsin A activity in melanoma cell lines.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine·2001
Separation of cathepsin A-like enzyme and the proteasome: evidence that lactacystin/beta-lactone is not a specific inhibitor of the proteasome.
The international journal of biochemistry & cell biology·2000
Effects of epsilon-aminocaproylaminoacids on prothrombin activation and thrombin activity.
Materia medica Polona. Polish journal of medicine and pharmacy·1999
The influence of epsilon-aminocaproic acid derivatives on the anticoagulant activity of heparin.
Roczniki Akademii Medycznej w Bialymstoku (1995)·1999
Inhibitors of pepsin, trypsin and chymotrypsin in seeds of plants consumed by humans and animals. I. Evaluation of pepsin, trypsin, and chymotrypsin inhibitors activity in seeds of 26 plant species.
Roczniki Akademii Medycznej w Bialymstoku (1995)·1999
Lactacystin, a specific inhibitor of the proteasome, inhibits human platelet lysosomal cathepsin A-like enzyme.
Biochemical and biophysical research communications·1997
[Risk of transmission of blood-derived pathogens by transfusion in Poland].
Acta haematologica Polonica·2020
[Emerging infectious diseases in the context of blood safety].
Acta haematologica Polonica·2020
Quo Vadis medycyno regeneracyjna?: Quo Vadis Regenerative Medicine?
Acta haematologica Polonica·2013
[RHnull syndrome--diagnostic and therapeutic problems].
Acta haematologica Polonica·1996
[Unclassified chronic myeloproliferative Ph(-); i(17q); +8 syndrome with mixed myelo-megakaryoblastic crisis--case report].
Acta haematologica Polonica·1996
Acute myelofibrosis in children: report on two cases.
Acta haematologica Polonica·1996
Investigation of chalcogen bonding in ebselen·DMAP co-crystals using synchrotron far-infrared spectroscopy.
Physical chemistry chemical physics : PCCP·2026
Vascular effects of micro- and nanoplastics in humans: Systematic review.
Kardiologia polska·2026
Solid state convergence to fluconazole monohydrate: Mechanochemical hydration, phase transitions, and solvent‑mediated conversion driving solubility.
Journal of pharmaceutical sciences·2026