Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Correlations in multi-locus genetic systems: a mathematical model.

C T Falk, H Falk

    Genetics
    |July 1, 1974
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Congruence and trajectories of device-measured and self-reported physical activity during therapy for early breast cancer.

    Breast cancer research and treatment·2021
    Same author

    Calcium electroporation for treatment of cutaneous metastases; a randomized double-blinded phase II study, comparing the effect of calcium electroporation with electrochemotherapy.

    Acta oncologica (Stockholm, Sweden)·2017
    Same author

    Der Orthopade·2017
    Same author

    Illegal import of bushmeat and other meat products into Switzerland on commercial passenger flights.

    Revue scientifique et technique (International Office of Epizootics)·2014
    Same author

    Chromoplasts of Tropaeolum majus L.: Structure and development.

    Planta·2014
    Same author

    Chromoplasts of Tropaeolum majus L.: Isolation and characterization of lipoprotein elements.

    Planta·2014
    Same journal

    Inherited long telomeres induce a genome-wide transcriptional response in budding yeast.

    Genetics·2026
    Same journal

    Adaptive Dynamics of Quantitative Traits in a Steadily Changing Environment.

    Genetics·2026
    Same journal

    Functional Landscape of Zebrafish Gonadotropins and Receptors: A Comprehensive Genetic Analysis.

    Genetics·2026
    Same journal

    Synergistic actions of Nup43 and Myosin VI drive actin cone assembly during Drosophila spermiogenesis.

    Genetics·2026
    Same journal

    Identification of two Cryptococcus neoformans heme transporters involved in Fhb1-mediated nitrosative stress protection in a fission yeast model.

    Genetics·2026
    Same journal

    Analysis of a hypomorphic mei-P26 mutation reveals coordination between developmental programming of germ cells and meiotic chromosome dynamics.

    Genetics·2026
    See all related articles

    This study introduces a spin model for calculating genetic correlations between alleles at different loci. Increased system size enhances allele correlation, with decay modeled by two exponentials.

    Area of Science:

    • Population Genetics
    • Statistical Mechanics
    • Theoretical Biology

    Background:

    • Understanding genetic linkage and allele correlations is crucial in population genetics.
    • Existing models often simplify complex interactions between multiple genetic loci.

    Purpose of the Study:

    • To present a novel spin model analogous to a multi-locus genetic model.
    • To calculate the correlation between allelic states at any two loci in a population at equilibrium.
    • To analyze the factors influencing the decay and strength of these correlations.

    Main Methods:

    • Development of a spin model with parallels to multi-locus genetic systems.
    • Mathematical formulation to calculate correlations between allelic states.
    • Analysis of correlation decay with distance and its dependence on system size.

    Related Experiment Videos

    Main Results:

    • The decay of correlation with distance is described by a linear combination of two exponentials.
    • Correlation between loci increases with the total number of loci in the system.
    • The model provides a framework for comparing theoretical predictions with experimental data.

    Conclusions:

    • The presented spin model offers a new perspective on genetic correlations in populations.
    • The model's predictions regarding correlation decay and system size dependence are highlighted.
    • Further experimental data is needed to validate the genetic relevance of this theoretical approach.