Related Experiment Video
Updated: Aug 19, 2026

Methods for ECG Evaluation of Indicators of Cardiac Risk, and Susceptibility to Aconitine-induced Arrhythmias in Rats Following Status Epilepticus
Published on: April 5, 2011
[Catecholamine metabolism in various compensatory manifestations of epilepsy patients]
Abstract:
The authors studied the catecholamine metabolism with an additional use of the function loadings by insulin and adrenalin in 77 epileptic patients who were ill for a long time and had marked disturbances in mental activity. The study was conducted in dynamics. The authors revealed a considerable activation of catecholamine metabolism in patients with acute psychotic states during dysphoria and in periods close to attacks against the background of typical, for the studied group, depression of the sympathoadrenalin system. The differences in the nature of reaction to the functional loadings, changing in various stages of the disease development and reflecting, to some extent, the compensatory possibilities of organism were registered.
Related Concept Videos
Adrenergic Neurons: Neurotransmission
Synthesis: Catecholamine synthesis requires tyrosine, which is taken...
Adrenergic Agonists: Indirect-Acting Agents
One mechanism involves depleting stored catecholamines by displacing them from synaptic vesicles. These agents, known as "displacers," are transported into vesicles at the expense of noradrenaline. Examples include amphetamine and tyramine, which lack a catechol moiety, resulting in prolonged action, improved oral bioavailability, and...
Drugs Affecting Neurotransmitter Release or Uptake
Parkinson's Disease: Treatment
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of its...
Epilepsy and Seizures: Overview
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
Antiepileptic Drugs: Glutamate Antagonists

