Methotrexate-agarose in the purification of dihydrofolate reductase

Crystal structures of chicken liver dihydrofolate reductase: binary thioNADP+ and ternary thioNADP+.biopterin complexes.

Biochemistry·1993

Crystal structure of chicken liver dihydrofolate reductase complexed with NADP+ and biopterin.

Biochemistry·1992

On the structure selectivity problem in drug design. A comparative study of benzylpyrimidine inhibition of vertebrate and bacterial dihydrofolate reductase via molecular graphics and quantitative structure-activity relationships.

Journal of medicinal chemistry·1989

Interaction of polyglutamyl derivatives of methotrexate, 10-deazaaminopterin, and dihydrofolate with dihydrofolate reductase.

Cancer research·1986

Inhibition of chicken liver dihydrofolate reductase by 5-(substituted benzyl)-2,4-diaminopyrimidines. A quantitative structure-activity relationship and graphics analysis.

Journal of medicinal chemistry·1986

Refined crystal structures of Escherichia coli and chicken liver dihydrofolate reductase containing bound trimethoprim.

The Journal of biological chemistry·1985

Mechanistic insights on HDAC6 ZnF UBP-Tau interaction through biophysical and computational approaches.

Methods in enzymology·2026

Methodological frameworks to probe histone acetylation-driven circuit plasticity in SYNGAP1-associated neurodevelopmental disorders.

Methods in enzymology·2026

Methodological approach to investigate peroxiredoxin 1 deacetylation by histone deacetylase 6.

Methods in enzymology·2026

Protocols for in vitro analysis of liquid-liquid phase separation of proteins.

Methods in enzymology·2026

Experimental approaches to study histone deacetylation in Caenorhabditis elegans.

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Methods in enzymology·2026

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Basic & clinical pharmacology & toxicology·2026

Beyond the Clock: Reprogramming Fertility in Diminished Ovarian Reserve.

Reproduction (Cambridge, England)·2026

Surgical sperm retrieval in cases with non obstructive azoospermia, comparative study between maldescended and normal positioned testis.

Urologia·2026

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International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics·2026

Dislocated and Disrupted: Experiences of Gay Intended Fathers with Pregnancy Loss via International Surrogacy.

Journal of homosexuality·2026

Calcium ionophore supplementation for immature oocytes and pentoxifylline supplementation for immotile sperms: A study of embryo quality of difficult cases in in vitro fertilization in a mouse model.

Journal of advanced pharmaceutical technology & research·2026

Related Experiment Videos

Methotrexate-agarose in the purification of dihydrofolate reductase

Related Concept Videos

Crystal structures of chicken liver dihydrofolate reductase: binary thioNADP+ and ternary thioNADP+.biopterin complexes.

Crystal structure of chicken liver dihydrofolate reductase complexed with NADP+ and biopterin.

On the structure selectivity problem in drug design. A comparative study of benzylpyrimidine inhibition of vertebrate and bacterial dihydrofolate reductase via molecular graphics and quantitative structure-activity relationships.

Interaction of polyglutamyl derivatives of methotrexate, 10-deazaaminopterin, and dihydrofolate with dihydrofolate reductase.

Inhibition of chicken liver dihydrofolate reductase by 5-(substituted benzyl)-2,4-diaminopyrimidines. A quantitative structure-activity relationship and graphics analysis.

Refined crystal structures of Escherichia coli and chicken liver dihydrofolate reductase containing bound trimethoprim.

Mechanistic insights on HDAC6 ZnF UBP-Tau interaction through biophysical and computational approaches.

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Protocols for in vitro analysis of liquid-liquid phase separation of proteins.

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Effects of Trazodone on Testicular Morphology, Sperm Parameters and Contractility of the Distal Cauda Epididymal Duct in Rats.

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Surgical sperm retrieval in cases with non obstructive azoospermia, comparative study between maldescended and normal positioned testis.

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Calcium ionophore supplementation for immature oocytes and pentoxifylline supplementation for immotile sperms: A study of embryo quality of difficult cases in in vitro fertilization in a mouse model.

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Methotrexate-agarose in the purification of dihydrofolate reductase

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