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Published on: June 23, 2015
Incidence and outcome of symptomatic urinary tract infection in children
Insights
This study found lower urinary tract infection (UTI) rates in children using strict criteria. Early radiological investigation is recommended after the first confirmed UTI in children.
Area of Science:
- Pediatrics
- Urology
- Infectious Diseases
Background:
- Symptomatic urinary tract infections (UTIs) are common in children.
- Accurate diagnosis and management are crucial to prevent complications.
Purpose of the Study:
- To determine the incidence of symptomatic UTIs in children under 15.
- To evaluate diagnostic methods and outcomes.
Main Methods:
- A 18-month prospective study in a single general practice.
- Diagnosis based on bacterial counts >100,000/ml in three consecutive urine samples.
- Analysis of radiological abnormalities, recurrence, and association with dysuria.
Main Results:
- UTI incidence: 1.7/1000 boys/year, 3.1/1000 girls/year.
- Three of 14 infected children had radiological abnormalities.
- Five children experienced recurrent infections; one had asymptomatic bacteriuria years later.
- Abacterial dysuria associated with upper respiratory tract infections.
Conclusions:
- Stricter diagnostic criteria may yield lower UTI incidence rates.
- Radiological investigation is recommended after the first confirmed UTI in children.
- Semiquantitative urine culture methods could improve diagnosis and management in general practice.
Abstract:
The incidence of symptomatic urinary tract infection in 2879 children aged under 15 years was studied over 18 months in a single general practice. Infection was diagnosed if bacterial counts in three consecutive samples exceeded 100,000/ml. The incidence of urinary tract infection was 1.7 per 1000 boys at risk per year and 3.1 per 1000 girls. These values are lower than those of comparable studies, possibly because of the stricter diagnostic criterion used in the study. Urinary pus cell counts were also carried out and sometimes found to be misleading. Of the 14 children found to have an infection, three had a radiological abnormality. Five of the children had a recurrence of infection within the first two years, and one an asymptomatic bacteriuria seven years after diagnosis. Only six out of 34 children presenting with dysuria had infected urine, and an association was discovered between abacterial dysuria (or the urethral syndrome) in the remainder and a concurrent upper respiratory tract infection. All children should undergo radiological investigation after their first confirmed infection. Diagnosis and management could be improved by providing all general practitioners with a semiquantitative method of urine culture such as the dip slide.
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Urinary Tract Infection I: Introduction
Urinary Tract Infection II: Pathophysiology
Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care
Urinary Tract Infection IV: Nursing Management
Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations
Urine Studies II: Urine Culture and Sensitivity Test

