[Gas-chromatographic method for determination of plasma lecithin-cholesterol acyl transferase (LCAT) activity]

A method is described for the determination of plasma lecythin-cholesterol acyl-transferase activity (LCAT), based on the measuring ot the free cholesterol concentration decrement in incubated plasma, with the aid of gas-liquid chromatography. Precision evaluation showed a sufficient reliability of the method, which is considered to be proposable for practical puopose. After verifying normal values in a group of healthy adults, plasma LCAT reduction in liver diseases, specially in the chronic hepatic disease, was confirmed.