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Lupus·2024

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The p90 ribosomal S6 kinase (RSK) inhibitor BI-D1870 prevents gamma irradiation-induced apoptosis and mediates senescence via RSK- and p53-independent accumulation of p21WAF1/CIP1.

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Caspase-2 is required for DNA damage-induced expression of the CDK inhibitor p21(WAF1/CIP1).

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Pifithrin-alpha protects against DNA damage-induced apoptosis downstream of mitochondria independent of p53.

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Hospital law: the changing scene.

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Clinical chemistry and laboratory medicine·2026

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