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Isolation of pathogenic treponemes from hare.

I Horvath, F Kemenes, L Molnar

Experientia

|March 15, 1979

Summary

A novel pathogenic treponeme species was identified from hares. This new treponeme caused lesions on rabbit scrotums after a 110-day incubation period, indicating potential zoonotic implications.

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Area of Science:

Veterinary Microbiology
Pathogen Discovery
Zoonotic Diseases

Background:

Treponemes are spirochetal bacteria known to cause various diseases in animals and humans.
The isolation of novel treponeme species is crucial for understanding disease pathogenesis and developing effective treatments.
Limited information exists on treponemal infections in lagomorphs, particularly concerning pathogenic species.

Purpose of the Study:

To isolate and identify a presumably new species of pathogenic treponeme from a diseased hare.
To experimentally infect a rabbit with the isolated treponeme to confirm its pathogenicity and characterize the resulting lesions.
To document the incubation period and clinical signs associated with this novel treponeme infection in rabbits.

Main Methods:

Isolation of treponemes from genital lesions of a hare (Lepus sp.).
Inoculation of a rabbit (Oryctolagus sp.) scrotum with the isolated treponeme.
Clinical observation and documentation of lesion development and incubation period.

Main Results:

A pathogenic treponeme was successfully isolated from a hare.
Experimental infection of a rabbit resulted in lesion development on the scrotum.
The incubation period for lesion development in the rabbit was observed to be 110 days.

Conclusions:

A presumably new species of pathogenic treponeme has been identified and isolated.
The isolated treponeme is capable of causing lesions in rabbits, suggesting potential cross-species infectivity.
Further research is warranted to fully characterize this novel treponeme and its public health significance.

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