[Ultrastructure of HeLa cells chromosomes by freeze-etching and shadow casting techniques (author's transl]

HeLa cells in metaphase arrest were studied by freeze-etching. The spiral organization of each chromatid appeared clearly, it was, however, impossible to visualize the inner structure of chromosomes. We have also analysed whole metaphase plates by the shadow casting technique; the results obtained do not seem to be useful for diagnostic application.