Seminal fluid prolactin: studies in normal subjects and in hypergonadotropic oligospermia

A sensitive radioimmunoassay was developed for the determination of seminal plasma prolactin levels. Prolactin added to normal or oligospermic seminal plasma was fully recoverable, indicating that the seminal plasma of oligospermic patients did not contain interfering substances. A gradient between seminal plasma blood serum prolactin was found in 54 health fertile subjects. No gradient was demonstrable among 13 infertile oligospermic patients who had normal levels of serum testosterone and luteinizing hormone but elevated levels of follicle-stimulating hormone.