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Pronase effect on pancreatic beta cell secretion and morphology

L Orci, M Amherdt, J C Henquin

    Science (New York, N.Y.)
    |May 11, 1973
    PubMed
    Summary

    Low concentrations of pronase enzyme reversibly enhance glucose-stimulated insulin release from pancreatic islets. This enzyme also alters beta cell structure, promoting tight junction development and secretory product accumulation.

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