[Changes in renal function in middle and old age established by isotopic nephrography]

The authors analyse the isotope-nephrographic examinations of 112 subjects, aged over 40, their clinical, paraclinical and X-ray examinations excluding an urological ailment. In 75 (67%) of the examined, isotope-nephrography proved to be pathological. Age advancing is accompanied by an increase of the patients with isotope-nephrogram deviations. Whereas at the age of 41--50, the pathological isotope nephrograms cover only 23.1 per cent of the examined, in the age groups over 60 that per cent is four times higher. Males are 1.8 times more frequently affected as compared with the females. After the qualitative and quantitative analysis three types of pathological curves were differentiated: with disturbed vascular and secretory phase: with disturbed vascular, secretory and excretory phase and nephrectomic type. In 57.3 per cent the deviations were bilateral and in 42l7 per cent--unilateral. The disturbances of the secretory function on the background of a reduced vascularization, is most frequently encountered (65.3%).