Reversible brain hyperthermia during audiogenic seizures in rats

Reversible brain hyperthermia during audiogenic seizures in rats. Acta Physiol. Pol., 1979, 30 (2): 273--277. Nine rats having inborn audiogenic susceptibility had chronically implanted Cu-constantan thermocouple and epidural EEG electrodes sewed into the skull. In freely moving animals audiogenic seizures were provoked by the use of common electric bell (approx. 100 dB). The EEG trace and brain temperature (with the accuracy of 0.05 degrees C) were recorded simultaneously during 1--8 hours. Temperature increases found during 23 audiogenic seizures were similar to those noted during intensive locomotor activity of animals without seizures. In thermoneutral environment (23 +/- 2 degrees C and humidity 65% +/- 10%) brain temperature never exceeded 41 degrees C.