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Retinal astrocytoma.

R C Ramsay, J L Kinyoun, C W Hill

    American Journal of Ophthalmology
    |July 1, 1979
    PubMed
    Summary
    This summary is machine-generated.

    A radioactive phosphorus uptake test suggested a benign retinal vascular tumor, but the final diagnosis was an astrocytic glioma. The tumor's vascularity likely caused the false-positive test result.

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    Area of Science:

    • Ophthalmology
    • Oncology
    • Pathology

    Background:

    • A 41-year-old male presented with an amelanotic tumor in the posterior fundus.
    • Differential diagnoses included benign retinal vascular tumor, amelanotic choroidal melanoma, and retinoblastoma.

    Observation:

    • A 6 x 6 x 5 mm amelanotic tumor was identified in the posterior fundus.
    • Clinical and fluorescein angiography suggested a benign vascular tumor.
    • An incisional radioactive phosphorus (32P) uptake test showed a 100% increase over the tumor compared to control quadrants.

    Findings:

    • Pathologic diagnosis revealed an isolated astrocytic glioma of the retina with minimal malignant potential.
    • The radioactive phosphorus uptake test yielded a false-positive result.

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    Implications:

    • The highly vascular nature of the astrocytic glioma likely contributed to the elevated 32P uptake.
    • This case highlights the importance of integrating multiple diagnostic modalities for intraocular tumors.
    • Careful interpretation of diagnostic tests is crucial, especially when tumor vascularity can influence results.