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Quantitative sacroiliac joint scintigraphy. A critical assessment
Arthritis and Rheumatism
|August 1, 1979
Summary
Quantitative sacroiliac joint scintigraphy (QSS) identifies sacroiliitis with high sensitivity. However, elevated sacroiliac joint-to-sacrum (SIS) ratios are not specific for inflammatory disease, appearing in other conditions too.
Area of Science:
- Nuclear Medicine
- Rheumatology
- Radiology
Background:
- Sacroiliac joint (SIJ) involvement is key in several inflammatory arthropathies.
- Quantitative sacroiliac joint scintigraphy (QSS) is a sensitive imaging technique for detecting SIJ inflammation.
Purpose of the Study:
- To evaluate the diagnostic specificity of QSS, specifically the sacroiliac joint-to-sacrum (SIS) ratio, for inflammatory SIJ disease.
Main Methods:
- Utilized quantitative sacroiliac joint scintigraphy (QSS) to measure sacroiliac joint-to-sacrum (SIS) ratios.
- Established an abnormal SIS ratio threshold of >= 1.40 for the QSS method.
Main Results:
- High SIS ratios (>= 1.40) correlate with roentgenographically evident sacroiliitis and early clinical sacroiliitis.
- Abnormal QSS findings, indicated by high SIS ratios, are not exclusive to inflammatory SIJ disease.
- Elevated SIS ratios were observed in conditions such as rheumatoid arthritis, degenerative lumbosacral spine abnormalities, and metabolic bone disorders.
Conclusions:
- QSS is a highly sensitive tool for detecting SIJ abnormalities.
- The specificity of QSS for inflammatory sacroiliitis is limited due to elevated SIS ratios in non-inflammatory conditions.
- Further scintigraphic studies are needed for other disorders with radiographic SIJ abnormalities before QSS can be definitively used as a diagnostic test for inflammatory SIJ disease.