Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Improved method for detecting hemagglutination by centrifugal analysis.

B Wenz, C S Feng, A Karmen

    Clinical Chemistry
    |September 1, 1979
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Activity tracker-based intervention to increase physical activity in patients with type 2 diabetes and healthy individuals: study protocol for a randomized controlled trial.

    Trials·2022
    Same author

    A large proportion of people who inject drugs are susceptible to hepatitis B: Results from a bio-behavioural study in eight German cities.

    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases·2017
    Same author

    Applying the Fisher score to identify Alzheimer's disease-related genes.

    Genetics and molecular research : GMR·2016
    Same author

    Holographic design of a two-dimensional photonic crystal of square lattice with pincushion columns and large complete band gaps.

    Optics express·2009
    Same author

    Jehovah's Witnesses and surgery.

    Hong Kong medical journal = Xianggang yi xue za zhi·2005
    Same author

    The use of a bacteria detection system to evaluate bacterial contamination in PLT concentrates.

    Transfusion·2004
    Same journal

    Comparison of Information-Dependent Acquisition and Sequential Window Acquisition of All Theoretical Mass Spectra for Untargeted Drug Testing on a Linear Ion Trap-Pulsing Quadrupole-Time of Flight Mass Spectrometer.

    Clinical chemistry·2026
    Same journal

    Patterns of One-Year Change in HbA1c and Continuous Glucose Monitoring (CGM) Metrics in Older Adults with Type 2 Diabetes.

    Clinical chemistry·2026
    Same journal

    TSH Pediatric Reference Intervals: Lack of CALIPER Applicability to US-Based Populations.

    Clinical chemistry·2026
    Same journal

    Rapid Detection of Hemoglobinopathy Variants Using One-Step Library Preparation and Nanopore Sequencing.

    Clinical chemistry·2026
    Same journal

    Editor's Note: Circulating Proteolytic Products of Carboxypeptidase N for Early Detection of Breast Cancer.

    Clinical chemistry·2026
    Same journal

    In Reply to Reflexing NT-proBNP for sFlt-1/PlGF Ratios That Fall into the Measurement Uncertainty for Preeclampsia Risk Classification.

    Clinical chemistry·2026
    See all related articles

    Centrifugal analysis offers a sensitive and specific method for detecting viral antigens and antibodies. This technique improves upon conventional hemagglutination tests by eliminating false positives and providing accurate, reproducible results.

    Area of Science:

    • Clinical chemistry
    • Immunology
    • Diagnostic techniques

    Background:

    • Conventional hemagglutination tests are widely used for antigen and antibody detection.
    • These methods can sometimes suffer from limitations in sensitivity, specificity, and reproducibility.
    • Improving diagnostic accuracy for infectious diseases and antigen detection is crucial.

    Purpose of the Study:

    • To evaluate centrifugal analysis as a novel method for detecting specific antigens and antibodies.
    • To compare the performance of centrifugal analysis with conventional hemagglutination techniques.
    • To assess the sensitivity, specificity, and reproducibility of this new diagnostic approach.

    Main Methods:

    • Utilized centrifugal analysis with standard hemagglutination reagents.

    Related Experiment Videos

  • Measured erythrocyte clearance rates (delta A/delta time) in a centrifugal field to differentiate reactions.
  • Applied the technique for detecting hepatitis B surface antigen, rubella virus antibody, and fibrin-related antigen.

    • Main Results:

    • Centrifugal analysis demonstrated higher sensitivity and specificity compared to conventional hemagglutination.
    • The technique effectively eliminated false-positive reactions.
    • Quantitative data obtained were accurate and reproducible, varying directly with antigen/antibody concentration.

    Conclusions:

    • Centrifugal analysis is a highly effective and accurate method for detecting viral antigens and antibodies.
    • This technique offers significant advantages over conventional hemagglutination, including improved diagnostic performance.
    • The method shows promise for reliable and reproducible clinical diagnostics.