Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Reference materials and reference methods in clinical chemistry.

D Stamm

    Journal of Clinical Chemistry and Clinical Biochemistry. Zeitschrift Fur Klinische Chemie Und Klinische Biochemie
    |May 1, 1979
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    [Severe local anesthetic intoxication in an infant undergoing circumcision].

    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie·2014
    Same author

    Healthcare-associated infection prevention in pediatric intensive care units: a review.

    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology·2012
    Same author

    [Influenza in pediatric intensive cure unit].

    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie·2004
    Same author

    [Pneumocystis carinii infections in a pediatric intensive care unit: a retrospective study 1980-2002].

    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie·2004
    Same author

    [Acute abdominal pain in children. Diagnostic orientation] .

    La Revue du praticien·2001
    Same author

    Postoperative ventilatory management with noninvasive positive-pressure ventilation in a child with a severe tracheomalacia.

    Anesthesiology·2001
    Same journal

    Determination of amniotic fluid acetylcholinesterase activity in the antenatal diagnosis of foetal malformations: the first ten years.

    Journal of clinical chemistry and clinical biochemistry. Zeitschrift fur klinische Chemie und klinische Biochemie·1990
    Same journal

    Antibodies as a source of analytical errors.

    Journal of clinical chemistry and clinical biochemistry. Zeitschrift fur klinische Chemie und klinische Biochemie·1990
    Same journal

    Determination of methotrexate in serum: the aca MTHO immunoassay and HPLC compared.

    Journal of clinical chemistry and clinical biochemistry. Zeitschrift fur klinische Chemie und klinische Biochemie·1990
    Same journal

    Improved sample and reagent pipetting with the MINILAB.

    Journal of clinical chemistry and clinical biochemistry. Zeitschrift fur klinische Chemie und klinische Biochemie·1990
    Same journal

    Enzyme immunoassay of testosterone using nitrocellulose discs as the solid phase.

    Journal of clinical chemistry and clinical biochemistry. Zeitschrift fur klinische Chemie und klinische Biochemie·1990
    Same journal

    Interference of immunoglobulins in the radioimmunoassay of human beta-endorphin.

    Journal of clinical chemistry and clinical biochemistry. Zeitschrift fur klinische Chemie und klinische Biochemie·1990
    See all related articles

    Clinical chemistry methods vary, causing significant differences in results. Reference materials and methods are crucial for improving accuracy and comparability in laboratory analyses, even with inherent limitations.

    Area of Science:

    • Clinical Chemistry
    • Analytical Chemistry
    • Laboratory Medicine

    Background:

    • Multiple analytical methods and instruments are used in clinical chemistry.
    • Discrepancies in results from different methods can have clinical significance.

    Purpose of the Study:

    • To describe reference materials and methods for clinical chemistry.
    • To discuss terminological differences and limitations in their application.
    • To explore compromises and error sources in reference systems.

    Main Methods:

    • Description of reference materials (calibration and control) and reference methods.
    • Discussion of ideal characteristics versus practical limitations.
    • Analysis of interlaboratory survey data using reference laboratories.

    Related Experiment Videos

    Main Results:

    • Significant differences in assigned values can occur between different clinical chemistry methods.
    • Reference materials and methods are essential for method comparison and validation.
    • Compromises in reference systems can still enhance analytical result reliability and comparability.

    Conclusions:

    • Reference materials and methods are vital for improving the reliability and comparability of clinical chemistry results.
    • Understanding and addressing limitations in reference systems is key to accurate laboratory diagnostics.
    • The described approaches offer pathways to enhance analytical performance in clinical laboratories.